This Week in Startups

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This Week in Startups

This Week in Startups

Luoja: Jason Calacanis

Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world’s greatest founders, operators, investors, and innovators.

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1398 jaksoa
The $60 billion resource hiding in space, and the start trying to mine it (feat. Matt Gialich, Astroforge) | E2268

The $60 billion resource hiding in space, and the start trying to mine it (feat. Matt Gialich, Astroforge) | E2268

This Week In Startups is made possible by:


Wispr Flow - https://wisprflow.ai/twist
Circle - http://circle.so/twist
Dee...

2026-03-28 01:40:54 01:39:16
Lataa
This Bittensor Subnet Could Cut Drug Discovery Costs in HALF | E2267

This Bittensor Subnet Could Cut Drug Discovery Costs in HALF | E2267

This Week In Startups is made possible by:
Luma AI - https://lumalabs.ai/twist
Every.io -  https://every.io
Lemon.io - https://Lemon...

2026-03-26 02:30:13 01:12:53
Lataa
$2.5B Chip Heist, The Future of American AI, and Purpose-Built Robots | This Week in AI Ep 6

$2.5B Chip Heist, The Future of American AI, and Purpose-Built Robots | This Week in AI Ep 6

This Week in AI sneak peak! If you enjoy the episode find us on Spotify, Apple podcasts and YouTube by looking up "This Week in AI" or by going to thi...

2026-03-26 00:01:51 01:15:24
Lataa
Compliance Startup Scandal... Is Delve Guilty? | E2266

Compliance Startup Scandal... Is Delve Guilty? | E2266

This Week In Startups is made possible by:

Northwest Registered Agent - https://northwestregisteredagent.com/twist
LinkedIn Jobs -...

2026-03-24 17:00:27 01:26:44
Lataa
The Drone Company Everyone Thought Was Illegal (Now Worth $4B+) | E2265

The Drone Company Everyone Thought Was Illegal (Now Worth $4B+) | E2265

This Week In Startups is made possible by:

Northwest Registered Agent - https://www.northwestregisteredagent.com/twist


2026-03-20 23:26:37 01:38:38
Lataa
How Robinhood became a $68B company w/ Vlad Tenev

How Robinhood became a $68B company w/ Vlad Tenev

This Week In Startups is made possible by:


Deel - https://deel.com/twist
LinkedIn Jobs - https://LinkedIn.com/twist.
I...

2026-03-18 21:20:17 00:49:41
Lataa
Are Brain-Computer Interfaces Actually Ready for Humans?

Are Brain-Computer Interfaces Actually Ready for Humans?

This Week In Startups is made possible by:
Caldera + Lab - https://CalderaLab.com/TWIST
Northwest Registered Agent - https://northwestregi...

2026-03-17 01:34:08 01:13:45
Lataa
One Genius Rule That Made This Coffee Brand Famous | EP 2262

One Genius Rule That Made This Coffee Brand Famous | EP 2262

Legendary British ad man Rory Sutherland invented a fake business on a podcast, a coffee shop appealing to the busy commuter called “Flat White or F**...

2026-03-14 03:27:07 01:30:27
Lataa
The Global Expansion of Self-Driving Vehicles

The Global Expansion of Self-Driving Vehicles

This Week In Startups is made possible by:


Circle - http://circle.so/twist


Sentry - http://Sentry.io

2026-03-11 23:55:38 01:09:18
Lataa
How agents will change banking forever | E2260

How agents will change banking forever | E2260

This Week In Startups is made possible by:
Northwest Registered Agent - ⁠⁠northwestregisteredagent.com/twist⁠⁠
Quo - ⁠⁠quo.com/TWiST⁠⁠

2026-03-10 03:06:00 01:00:38
Lataa
Wisdom of the $TAO: the future is decentralized AI

Wisdom of the $TAO: the future is decentralized AI

This Week In Startups is made possible by:
Every Banking - https://Every.io
https://Lemon.io - Lemon.io/twist
Wispr Flow - https://w...

2026-03-07 01:19:04 01:08:26
Lataa
Is Anthropic Making the Biggest Mistake in AI History | E2258

Is Anthropic Making the Biggest Mistake in AI History | E2258

This Week In Startups is made possible by:
Plaud - Plaud.ai/twist
LinkedIn Jobs - https://LinkedIn.com/twist.
Deel - https://deel.co...

2026-03-05 02:26:06 01:20:55
Lataa
How the OpenClaw foundation bullet-proofed its future (w/Dave Morin) | E2257

How the OpenClaw foundation bullet-proofed its future (w/Dave Morin) | E2257

This Week In Startups is made possible by:Circle — http://circle.so/twistHubspot Creators — http://clickhubspot.com/twist2Uber AI Solutions — http://u...

2026-03-03 02:33:43 01:14:43
Lataa
The Biggest Private Funding Round in History | E2256

The Biggest Private Funding Round in History | E2256

This Week In Startups is made possible by:
Deel - http://deel.com/twist
Wispr Flow - https://wisprflow.ai/twist
Luma AI - https://lu...

2026-02-28 02:44:30 01:20:17
Lataa
Behind the Scenes with an early OpenClaw contributor! | E2252

Behind the Scenes with an early OpenClaw contributor! | E2252

This Week In Startups is made possible by:


Lemon IO - https://Lemon.io/twist
Every.io - https://every.io
Sentry.io- h...

2026-02-26 03:29:31 01:22:11
Lataa
Kill Your Startup’s Knowledge Chaos with OpenClaw (with Oliver Henry and Jeff Weisbein) | E2254

Kill Your Startup’s Knowledge Chaos with OpenClaw (with Oliver Henry and Jeff Weisbein) | E2254

This Week In Startups is made possible by:Caldera Lab - [calderalab.com/twist](https://calderalab.com/twist)Iru - [iru.com](http://Iru.com/twist)Linke...

2026-02-24 03:20:17 01:18:57
Lataa
We Asked 3 Experts How to Get More Value out of OpenClaw | E2253

We Asked 3 Experts How to Get More Value out of OpenClaw | E2253

This Week In Startups is made possible by:
Gusto - https://Gusto.com/twist
Circle - https://circle.so/twist
Northwest Registered Age...

2026-02-21 02:07:57 01:08:36
Lataa
When Will Openclaw go Mainstream? | E2252

When Will Openclaw go Mainstream? | E2252

This Week In Startups is made possible by:


Gusto - Try Gusto today and get 3 months free at gust.com/twist


Cru...

2026-02-19 04:11:39 01:02:26
Lataa
Will OpenAI Tank OpenClaw? | E2251

Will OpenAI Tank OpenClaw? | E2251

Will OpenAI Tank OpenClaw? | E2251
This Week In Startups is made possible by:
Northwest Registered Agent - https://www.northwestregistered...

2026-02-17 05:42:08 01:26:33
Lataa
OpenClaw is Our Friend Now | E2250

OpenClaw is Our Friend Now | E2250

This Week In Startups is made possible by:


Sentry - http://sentry.io/twist


Circle - http://Circle.so/twist

2026-02-14 04:52:36 01:06:28
Lataa
Why J-Cal Invested to 200K in a former Employee | E2249

Why J-Cal Invested to 200K in a former Employee | E2249

This Week In Startups is made possible by:


NetSuite - https://www.netsuite.com/twist


Luma AI - https://lumalab...

2026-02-13 01:50:17 00:40:27
Lataa
How These 3 Founders are building on Open Claw | E2248

How These 3 Founders are building on Open Claw | E2248

This Week In Startups is made possible by:


Hubspot - http://clickhubspot.com/twist2


Deel - http://deel.com/twi...

2026-02-12 03:32:23 00:45:04
Lataa
Does Clawdbot (OpenClaw) Need Eyes? (feat. Alex Finn and Matt Van Horn) | E2247

Does Clawdbot (OpenClaw) Need Eyes? (feat. Alex Finn and Matt Van Horn) | E2247

This Week In Startups is made possible by:


LinkedIn - http://linkedin.com/twist


Every.io - http://every.io/

2026-02-10 02:24:35 01:07:58
Lataa
We built OpenClaw Ultron to replace 20 people at our company | E2246

We built OpenClaw Ultron to replace 20 people at our company | E2246

This Week In Startups is made possible by:


Crusoe Cloud - https://crusoe.ai/savings


Lemon IO - https://Lemon.i...

2026-02-07 02:22:25 01:10:51
Lataa
Savvy is HQ Trivia + Wordle (feat. Scott Rogowsky) | E2245

Savvy is HQ Trivia + Wordle (feat. Scott Rogowsky) | E2245

This Week In Startups is made possible by:


Circle - http://Circle.so/twist


Caldera Lab - http://calderalab.com...

2026-02-05 01:55:29 00:53:41
Lataa
Where early-stage founders MUST focus to success | E2244

Where early-stage founders MUST focus to success | E2244

This Week In Startups is made possible by:


Quadratic - http://quadratic.ai/twist


Today’s show: 

<...

2026-02-03 23:52:08 01:07:08
Lataa
SpaceX + xAI deal gets us one step closer to Musk Industries | E2243

SpaceX + xAI deal gets us one step closer to Musk Industries | E2243

This Week In Startups is made possible by:


Uber - http://uber.com/twist


Deel - http://deel.com/twist

2026-02-03 05:19:20 01:02:11
Lataa
AI Bots Take Over | E2242

AI Bots Take Over | E2242

This Week In Startups is made possible by:
Deel - http://deel.com/twist
LinkedIn Jobs - http://linkedin.com/twist
Northwest Register...

2026-01-31 04:18:48 01:28:26
Lataa
How decriminalization led to an explosion in cannabis startups (Feat. Ford Smith, Andrew Duffy, and Socrates Rosenfeld) | E2241

How decriminalization led to an explosion in cannabis startups (Feat. Ford Smith, Andrew Duffy, and Socrates Rosenfeld) | E2241

This Week In Startups is made possible by:


Gusto - http://Gusto.com/twist


Zite - http://zite.com/twist
<...

2026-01-29 03:30:41 00:55:31
Lataa
Clawdbot is an inflection point in AI history | E2240

Clawdbot is an inflection point in AI history | E2240

This Week In Startups is made possible by:


Quo - http://quo.com/TWiST


Lemon IO - https://lemon.io/twist
...

2026-01-27 04:02:57 01:02:14
Lataa
Why You’ll Choose an AI Doctor (feat. Fred Almeida and Max Weiss) | E2239

Why You’ll Choose an AI Doctor (feat. Fred Almeida and Max Weiss) | E2239

This Week In Startups is made possible by:
Sentry.io - sentry.io/twist
Hubspot - clickhubspot.com/twist2
Northwest Registered Agent...

2026-01-24 03:44:12 01:03:23
Lataa
From Blood Transfusions to Burritos, How Zipline is Automating Delivery | E2238

From Blood Transfusions to Burritos, How Zipline is Automating Delivery | E2238

This Week In Startups is made possible by:


Northwest Registered Agent - www.northwestregisteredagent.com/twist


...

2026-01-22 01:28:05 01:03:33
Lataa
How startups suddenly became “cool” in Japan (feat. Shin Takamiya of Globis Capital) | E2237

How startups suddenly became “cool” in Japan (feat. Shin Takamiya of Globis Capital) | E2237

This Week In Startups is made possible by:


Circle.so - http://Circle.so/twist


Deel - http://deel.com/twist

2026-01-21 01:54:30 00:57:35
Lataa
Avoiding buzzwords and marketing-speak (feat. Thomas McInerney) | E2236

Avoiding buzzwords and marketing-speak (feat. Thomas McInerney) | E2236

This Week In Startups is made possible by:


Lemon.io - https://lemon.io/twist


Deel - http://deel.com/twist

2026-01-16 22:27:18 01:03:25
Lataa
Japan’s Startup Revolution (feat. Kathy Matsui) | E2235

Japan’s Startup Revolution (feat. Kathy Matsui) | E2235

This Week In Startups is made possible by:


Every.io - http://every.io/


LinkedIn Jobs - https://www.linkedin.co...

2026-01-15 01:28:33 01:07:43
Lataa
How to Make Billions from Exposing Fraud | E2234

How to Make Billions from Exposing Fraud | E2234

This Week In Startups is made possible by:


Netsuite - https://www.netsuite.com/twist


LumaAi - https://lumalabs...

2026-01-14 00:59:30 01:05:16
Lataa
Secrets of Startup Recruiting in the US AND Japan! (feat. Sho Takei) | E2233

Secrets of Startup Recruiting in the US AND Japan! (feat. Sho Takei) | E2233

This Week In Startups is made possible by:


Northwest Registered Agent - www.northwestregisteredagent.com/twist


...

2026-01-13 02:40:59 00:52:02
Lataa
Jason’s Top CES Products and Takeaways | E2232

Jason’s Top CES Products and Takeaways | E2232

This Week In Startups is made possible by:


Hubspot - http://clickhubspot.com/twist1


Circle.so - http://circle....

2026-01-10 05:05:23 01:09:08
Lataa
AI makes you more creative, AI Roundtable with Steven Johnson and Grant Lee | E2231

AI makes you more creative, AI Roundtable with Steven Johnson and Grant Lee | E2231

This Week In Startups is made possible by:


Gusto - https://www.gusto.com/twist


Lemon IO -  https://lemon.io/tw...

2026-01-08 03:42:58 01:06:29
Lataa
2026 Starts with a bang: META AI Drama and Nvidia’s $20B Groq Acquisition | E2230

2026 Starts with a bang: META AI Drama and Nvidia’s $20B Groq Acquisition | E2230

This Week In Startups is made possible by:


Crusoe Cloud - https://crusoe.ai/build


Uber - http://uber.com/twist...

2026-01-06 03:02:38 00:54:39
Lataa
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